Below is information about the research studies our lab is conducting. Please read the brief description of the study and if you are interested in volunteering, please contact us at (313) 577-2790 or tnp2lab_volunteer@lists.wayne.edu.

effects of thc on retention of memory for fear extinction learning in ptsd: r33 study

*We are actively recruiting for this study.

This clinical trial will examine how a type of drug called cannabinoids (e.g., marijuana, THC) effects symptoms of posttraumatic stress disorder (PTSD) during and after prolonged exposure (PE) therapy. PE is a first-line PTSD treatment which involves working with a therapist to emotionally process traumatic experiences and reduce fear and anxiety. During some of the therapy sessions, you may be asked to ingest a capsule containing either dronabinol, an FDA-approved cannabinoid drug, or placebo (sugar pill). This study will also examine effects of cannabinoids and PE therapy on brain activation during magnetic resonance imaging (MRI) scanning. The information gained from this study could lead to the development of new treatments for persons who suffer from PTSD. If you complete all study procedures, you will be paid $500 for your participation.

There are 17 total visits, including:

• Questionnaires about your health, background, and life experiences

• MRI scans and virtual reality tasks

• Free PE therapy sessions

• Follow-up questionnaires 1- and 3-months after treatment

If you are interested in participating in this trial, please complete the confidential, online eligibility survey, here.

Learn more about this research study at ClinicalTrials.gov