Below is information about the research studies our lab is conducting. Please read the brief description of the study and if you are interested in volunteering please contact us at (313) 577-5404 or tnp2lab_volunteer@lists.wayne.edu.

effects of thc on retention of memory for fear extinction learning in ptsd: r61 study

*We are actively recruiting for this study.

This study will examine the effects of a drug on behavior, fear conditioning, and emotions in trauma-exposed volunteers and participants with symptoms of posttraumatic stress disorder. 

You will undergo a 3 hour psychiatric and medical screening visit before being accepted in the study. If you are selected to participate, you will participate in 4 more sessions. The first 3 sessions will be scheduled on consecutive days. Approximately, 1 week later you will complete the final session. During these sessions you will be performing some computer tasks in an MRI scanner. An MRI scanner is a large magnet that lets us take pictures of your brain. There is no radioactive dye or x-rays used.  During some of these tasks you will experience aversive stimuli (e.g. virtual snake), which will be unpleasant. We will measure physiological responding through electrodes placed on your skin during each visit. During the third visit you may be asked to ingest a capsule containing either Marinol (THC, cannabinoid, a marijuana-like drug approved by the Food & Drug Administration) or Placebo (sugar). If you do receive a capsule you will not be allowed to drive yourself home, so should arrange for transportation or a taxi can be called for you and will be paid for by the study. During these visits, you might get your blood drawn as well. An IV may be placed in your arm during visits 3, 4, and 5. At the end of the finial visit, we will hold a debriefing session in which we will explain the study procedures to you in more detail. If you complete all study procedures, you will be paid up to $110-$260 for your participation.

effects of faah genotype on fear-related brain activation

*We are actively recruiting for this study.

This study will examine the effects of genetics and emotions in healthy volunteers.

You will undergo a 1 hour psychiatric and medical screening visit before being accepted in the study.  If you are selected to participate, you will participate in 2 more sessions (1 hour each).  Sessions need be scheduled on consecutive days. During these sessions you will be performing some tasks in an MRI scanner.  An MRI scanner is a large magnet that lets us take pictures of your brain.  There is no radioactive dye or x-rays used.  During some of these tasks you will experience aversive stimuli (e.g. loud noise, snake), which will be unpleasant, but not painful. We will measure physiological responding through electrodes placed on your skin during each visit. If you complete all study procedures, you will be paid up to $50 for your participation.

Childhood adversity and brain and behavioral development in children

*We are NOT actively recruiting for this study at this time.

This study will examine brain systems that underlie learning and memory in 6-9 year old children who have or have not experienced adversity (violence, abuse, medical trauma) 

The experiment happens over the course of one weekend (Saturday and Sunday), for about 3.5 each day. Caregiver and child will attend both sessions. On Saturday, the child will complete several games that test learning and memory on the computer and on an advanced virtual reality platform - that makes it more fun for kids. We will also interview caregiver and child about life experiences, emotions, and family life. The child will also watch a video of what it’s like for a child to have an MRI brain scan. The MRI will happen on the second day. On Sunday’s session, we will practice laying still in the scanner with a mock or practice MRI machine. The child will be laying down in the real MRI machine for about an hour. During the scan, they will play some games and watch a movie. There will also be times when they can lay awake quietly and relax. For participating, you will receive a picture of your child’s brain and $110 for each visit ($220 for the entire weekend). Additionally, you will receive a $30 giftcard for completing a sleep take-home packet on Saturday evening and Sunday morning. For more information, please contact Farrah at 586-23-CLIMB (25462). 

MRI is a large magnet that allows us to take pictures of the brain. It is completely non-invasive, with no radioactive dye or x-ray. For more information about what it’s like for a child to have an MRI brain scan, please see the link below:

http://www.tnp2lab.org/think-study-video/